This is to inform that due to some circumstances beyond the organizer control, “International Conference on Medicinal Chemistry, Computer Aided Drug Design and Delivery” (MCADD 2023) Hybrid event during September 14-16, 2023 at Valencia, Spain has been postponed. The updated dates and venue will be displayed shortly.
Your registration can be transferred to the next edition, if you have already confirmed your participation at the event.
For further details, please contact us at medicinal-chemistry@magnusconference.com or call + 1 (702) 988 2320.
N-ribosylation and N-mannosylation compounds have a great role in compounds activity as anticancer. The reaction of 2-thioxo-4-thiazolidinone (rhodanine) derivatives, as aglycon part, was done with ribofuranose and mannopyranose sugars (glycone part) followed by deacetylatio [....] » Read More
A significant threat to global efforts to control and eradicate malaria is the evolution and spread of treatment resistance in Plasmodium falciparum, the parasite that causes the most dangerous form of the disease. Artemisinin and its derivatives are currently the cornerstones of [....] » Read More
Escherichia coli, Salmonella enterica, Acinetobacter baumannii, Pseudomonas aeguginosa, Enterococcus faecium, and Klebsiella pneumonia-mediated infections were not cured by antibiotics due to multiple large and small MDR plasmids containing >10 MDR (bla, cat, strA/B, aac, [....] » Read More
Title : Transition metal complexes/Organometallic compounfs as anticancer drugs
Prakash kinthda, Nims university,jaipur,rajasthan, India
Cancer is a dreadful disease and any practical solution in combating this disease is of paramount importance to public health. Cancer patients have burdened by drug induced toxic side effects, and no turned to seek help from the complementary and alternative medicine hoping for [....] » Read More
Title : Tackling mycobacterium tuberculosis resistance with tailored isatin-pyrimidine hybrids enoyl acyl carrier protein reductase (Inha)
Amgad Albohy, The British University in Egypt (BUE), Egypt
Tuberculosis is a worldwide problem that imposes a burden on the economy due to the continuous development of resistant strains. The development of new antitubercular drugs is a need and can be achieved through the inhibition of druggable targets. Mycobacterium tuberculosis& [....] » Read More
Title : Synthesis, antibacterial activity of 3-amino 5-methoxyl-2-methyl quinazolin-4(3H)-one an amino-6-methoxyl-2-methyl of 4H–benzo[d] [1,3]–oxazine–4–one
Osarumwense Peter Osarodion, Ondo State University of Sciences and Technology, Nigeria
Introduction: Quinazolinone derivatives represent one of the most active classes of compounds possessing a wide spectrum of biological activity. They are widely used in pharmaceuticals and agrochemicals. Methods: The condensation of 2-amino-methyl-5-dimethoxybenzoate with acetic [....] » Read More
Title : Abbott diagnostics: COVID-19 inactivation, nucleocapsid antigen automated immunoassay development, and variant testing for automated and lateral flow assays binaxnow™ and panbio™
Philip M Hemken, Abbott Laboratories, United States
Dr. Hemken will describe the viral inactivation of SARS?CoV?2 with the detergent Tergitol 15?S?9. In the process of developing a prototype immunoassay on the ARCHITECT automated analyzer for detecting the SARS?CoV?2 antigen, we discovered heat inactivation reduced the detection [....] » Read More
Title : A qsar survey on tyrosine kinase inhibitors
Atefeh Hajiagha Bozorgi, Faculty of pharmacy, Iran (Islamic Republic of)
The epidermal growth factor receptor (EGFR) is an essential receptor tyrosine kinase (RTK) that regulates cell proliferation and differentiation and its abnormal activation contributes to a variety of human cancers. Among the various methods of drug design, computer-aided drug de [....] » Read More
Title : HDAC inhibitors with non-hydroxamate warhead
Franz-Josef Meyer-Almes, Darmstadt University of Applied Sciences, Germany
Compounds with a thiazolidinedione (TZD) functionality, so-called glitazones, are known as PPAR?-activators and anti-diabetic drugs. The mode of action of these glitazones has extensively be investigated and is known in great structural detail. PPAR? is a prominent target with a [....] » Read More