Potent Compounds and Emerging Targets

Pharmacology is the study of how chemicals interact with live organisms to impact their biochemical functioning. Potency is a measure of drug activity stated in terms of the amount necessary to generate an effect of a specific intensity in the discipline of pharmacology. At low doses, a highly potent medicine elicits a bigger reaction, whereas a substance of lower strength elicits a smaller response at identical concentrations. The design and implementation of an effective potent compound safety programme should follow the same basic process as traditional industrial hygiene programmes: hazards should be anticipated, activities with the potential for drug exposure should be identified and evaluated, and finally, these exposures should be controlled. If a chemical has an eight-hour time-weighted average occupational exposure limit (OEL) of 10 g/m3 or less, it is considered powerful in pharmacological terms. However, there is no formally agreed-upon definition of what defines a "highly potent" molecule at the OEL level. Individual risk assessors may classify the same substance differently, adding to the uncertainty.

• Compound Potency
• Potent Dual-Targeting Compound
• Discovery A Potent Lead Compound